PATHOGEN

Infect. Mutate. Spread.

An action roguelite where you are the virus. Break into a host, tear through eight organs, outsmart an immune system that learns how you play, then take your infection to the whole world.

Coming soon to iPhone · iPad · Mac

What is Pathogen?

Most games ask you to stop the outbreak.
This one makes you the outbreak.

Pathogen is a fast, top-down action roguelite. You're a single virion dropped into a living host, and every cell in that body wants you dead. Shoot, dash and mutate your way through organ after organ, picking up traits that stack into ridiculous builds. Each run is one generation of your virus. Win or lose, your lineage carries on, mutates, and comes back stronger.

8organs, each with a boss
4viruses that play differently
35traits in 7 tiers
3Game Modes

How a run plays

Infect a host. Take it over, organ by organ.

Every run starts in the nasal passage and pushes deeper toward the brain. The body fights back harder the further you go.

Infect

Pick a host, each with a hidden genome of strengths and weaknesses, and drop into its nose.

Fight

Auto-fire into waves of real immune cells: neutrophils, macrophages, B cells, NK cells and Killer T cells.

Mutate

Grab traits as you go: burning, poison, chill, shock, bouncing and orbiting shots. Stack them into a build.

Spread

Beat each organ's guardian boss to break through to the next organ: lungs, bloodstream, lymph node, gut, liver, bone marrow, brain.

Four viruses

Evolve into something nastier

Every lineage starts as Influenza A. Mutations can turn it into three other viruses, each with its own skills, ultimate and playstyle.

Influenza A fighting a crowd of immune cells

The Shapeshifter

Influenza A

Your shot type keeps drifting, and Antigenic Shift fires every mutation at once. Unpredictable and always changing.

Retrovirus with an army of captured cells

The Turncoat

Retrovirus

Stores the cells it kills and releases them as an army that fights for you. Captured macrophages even tank hits on your behalf.

Filovirus making a boss bleed

The Hemorrhager

Filovirus

Every hit can make cells bleed. Hemorrhage bleeds a whole crowd at once, and bleeding cells hit you softer.

Halovirus fighting in the bloodstream

The Superspreader

Halovirus

Fast and fragile. Cycles through Swarm, Fury and Ghost forms, and infected cells burst onto everything next to them.

A boss fight full of projectiles

A living body

The immune system adapts to you

Dominate too hard and the body notices. Detection rises, Killer T cells start hunting you room to room, and a Cytokine Storm sends crimson cells built to resist your exact build.

  • A guardian boss in every organ, with shield and frenzy phases
  • Tumors that grow and metastasize into the next organ
  • Elite cells with affixes like Vampiric, Splitting and Shielded
  • Rival viruses competing for the same host
  • Medicine: antivirals, vaccine boosters and interferon
The virus surrounded by dozens of cells

Build crafting

Stack traits into chaos

35 traits, each in 7 tiers from common to prismatic. Pick the same one again and it stacks. Grab a power-up for a few seconds of Chain Lightning, Fire Cross flamethrowers or Frost Aura, or find the rare CRISPR that makes you invincible.

Three Game Modes

Infect a host, then infect the world

Pick how you want to spread.

Infect

The main mode. Fight through the eight organs, earn XP and grow your lineage one generation at a time.

Pandemic

The story mode. Pick a city on the world map and infect it run by run. Every city fights back with its own policies.

Endless

Wave after wave in the deepest organ you've reached, with a boss every few sets. How long can you last?

The Pandemic world map, mostly infected

Pandemic Game Mode

Take cities, then whole continents. Politicians, doctors and the public respond as your infection spreads: lockdowns, mask mandates, booster campaigns and more, each changing how your runs play.

Between runs

Every run makes you stronger

Even a failed infection leaves something behind.

Skill trees

Spend points across three branches: active skills, passives and capstones.

Gear

Collect, equip, enhance and merge gear into higher tiers, and sometimes it mutates.

Family tree

Each run is a generation. Your lineage mutates, switches viruses and inherits bonuses.

Petri Lab

Permanent upgrades bought with the nucleotides you collect.

Challenges

Daily and weekly goals with rewards to collect.

The Codex

Real biology behind every cell, virus, organ and treatment you meet.

Play your way

Touch, controller, keyboard or mouse

Touch controls on iPhone and iPad. Full support for Xbox, PlayStation, Switch Pro and MFi controllers with remappable buttons. Keyboard and mouse on Mac, or a keyboard on iPad.

See all controls See every feature

Screenshots

A closer look

Be patient zero

Pathogen is in beta on iPhone and iPad. Join the community to play early, share your runs and help shape the game.